[Similar features in mechanisms of translation initiation of mRNAs in eukaryotic and prokaryotic systems]

Mol Biol (Mosk). 2006 Jul-Aug;40(4):694-702.
[Article in Russian]

Abstract

Using as examples non-canonical features of translation initiation for some bacterial and mammalian mRNAs with unusual 5'- untranslated regions (5'-UTR) or lacking these regions (leaderless mRNAs), the authors of this review discuss similarities in mechanisms of translation initiation on prokaryotic and eukaryotic ribosomes.

Publication types

  • Comparative Study
  • English Abstract
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • 5' Untranslated Regions
  • Animals
  • Bacteria / genetics
  • Bacteria / metabolism
  • Base Sequence
  • Codon, Initiator*
  • Eukaryotic Cells / physiology*
  • Eukaryotic Initiation Factors / metabolism
  • Molecular Sequence Data
  • Prokaryotic Cells / physiology*
  • Protein Biosynthesis / physiology*
  • RNA Viruses / genetics
  • RNA, Messenger / physiology*
  • RNA, Viral / physiology
  • Ribosomes / physiology*

Substances

  • 5' Untranslated Regions
  • Codon, Initiator
  • Eukaryotic Initiation Factors
  • RNA, Messenger
  • RNA, Viral