Probing, inhibition, and crystallographic characterization of metallo-beta-lactamase (IMP-1) with fluorescent agents containing dansyl and thiol groups

ChemMedChem. 2006 Sep;1(9):969-72. doi: 10.1002/cmdc.200600115.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crystallography, X-Ray
  • Dansyl Compounds / chemical synthesis
  • Dansyl Compounds / chemistry*
  • Dansyl Compounds / pharmacology*
  • Enzyme Inhibitors / chemical synthesis
  • Enzyme Inhibitors / chemistry*
  • Enzyme Inhibitors / pharmacology*
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry*
  • Indicators and Reagents
  • Models, Molecular
  • Serratia marcescens / drug effects
  • Serratia marcescens / enzymology
  • Sulfhydryl Compounds / chemical synthesis
  • Sulfhydryl Compounds / chemistry*
  • Sulfhydryl Compounds / pharmacology*
  • beta-Lactamase Inhibitors*
  • beta-Lactamases / chemistry*

Substances

  • Dansyl Compounds
  • Enzyme Inhibitors
  • Fluorescent Dyes
  • Indicators and Reagents
  • Sulfhydryl Compounds
  • beta-Lactamase Inhibitors
  • beta-lactamase IMP-1
  • beta-Lactamases