Abstract
Between 1998 and 2003 the rate of erythromycin resistance among pneumococci in Spain was 34.4%. Although the MLS(B) phenotype was prevalent (94.7%), the rate of the M phenotype increased from 3.3% to 8.9% (P < 0.01). Clonal dissemination of mef(E)-carrying strains of serotype 14 variant of the Spain(9V)-3 clone was the major contributor to this increase.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology*
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Bacterial Proteins / genetics
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Drug Resistance, Bacterial
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Erythromycin / pharmacology*
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Humans
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Membrane Proteins / genetics
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Pneumococcal Infections / epidemiology
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Pneumococcal Infections / microbiology
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Spain / epidemiology
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Streptococcus pneumoniae / classification*
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Streptococcus pneumoniae / drug effects*
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Streptococcus pneumoniae / genetics
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Streptococcus pneumoniae / isolation & purification
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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MefA protein, Streptococcus
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Membrane Proteins
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Erythromycin