A new dimension of sensory dysfunction: stereopsis deficits in schizophrenia

Biol Psychiatry. 2006 Dec 1;60(11):1282-4. doi: 10.1016/j.biopsych.2006.03.064. Epub 2006 Aug 30.

Abstract

Background: Schizophrenia is a neurocognitive disorder with a wide range of cognitive and sensory impairments. Early visual processing has been shown to be especially impaired. This article investigates the integrity of binocular depth perception (stereopsis) in schizophrenia.

Methods: Seventeen schizophrenia patients and 19 healthy control subjects were compared on the Graded Circles Stereo Test. Results of stereoacuity were compared between patients and control subjects using t test.

Results: Schizophrenia patients demonstrated significantly (p = .006) reduced stereoacuity (mean = 142 arcseconds) versus control subjects (mean = 55 arcseconds). At the normative level for adults, patients performed below chance.

Conclusions: These findings demonstrate an impairment of binocular depth perception and further confirm deficits of early visual processing in schizophrenia. Findings are discussed in context of magnocellular/dorsal stream processing with implications for visual processing and cognitive deficits.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Depth Perception / physiology*
  • Female
  • Humans
  • Male
  • Photic Stimulation / methods
  • Reproducibility of Results
  • Schizophrenia / complications*
  • Sensation Disorders / etiology*
  • Statistics, Nonparametric