SPEED: a molecular-evolution-based database of mammalian orthologous groups

Bioinformatics. 2006 Nov 15;22(22):2835-7. doi: 10.1093/bioinformatics/btl471. Epub 2006 Sep 11.

Abstract

Motivation: The abundance of nucleotide sequence information available has expanded horizons of inquiry for molecular evolution; however, the full potential of whole-genome analysis has not been realized because of inadequate tools. Here, we present one of the first toolkits to aid multidisciplinary high-throughput analysis.

Summary: SPEED was created to integrate molecular evolutionary data with existing genetic resources and provide a straightforward user interface to 17,352 orthologous gene groups, containing representatives from eight mammalian species and an avian outgroup.

Availability: See http://bioinfobase.umkc.edu/speed/ for access.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Animals
  • Computational Biology / methods*
  • Databases, Genetic
  • Databases, Protein*
  • Evolution, Molecular*
  • Genome
  • Humans
  • Phylogeny
  • Sequence Alignment
  • Software