Aortic root aneurysm due to donor cystic medial degeneration after heart-lung transplantation

Lois U Nwakanma; Luca A Vricella; John V Conte; Robert C Robbins

doi:10.1016/j.healun.2006.06.019

Aortic root aneurysm due to donor cystic medial degeneration after heart-lung transplantation

J Heart Lung Transplant. 2006 Oct;25(10):1273-5. doi: 10.1016/j.healun.2006.06.019. Epub 2006 Sep 12.

Authors

Lois U Nwakanma¹, Luca A Vricella, John V Conte, Robert C Robbins

Affiliation

¹ Division of Cardiac Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA.

PMID: 17045942
DOI: 10.1016/j.healun.2006.06.019

Abstract

A patient presented with symptomatic aortic root enlargement 5 years after combined heart and double-lung transplantation for cystic fibrosis, requiring homograft aortic root replacement. Histologic examination of the resected aneurysm showed cystic medial degeneration with no evidence of infectious or atherosclerotic process. Surgical options and potential role of immunosuppressive therapy after homograft implantation are discussed.

Publication types

Case Reports

MeSH terms

Adult
Aorta / transplantation
Aorta, Thoracic / diagnostic imaging
Aortic Aneurysm / diagnostic imaging
Aortic Aneurysm / etiology*
Aortic Aneurysm / surgery
Aortic Diseases / complications*
Aortic Diseases / surgery
Cystic Fibrosis / surgery*
Female
Heart-Lung Transplantation / adverse effects*
Humans
Image Processing, Computer-Assisted
Male
Middle Aged
Radiography, Thoracic
Tissue Donors*
Tomography, X-Ray Computed
Transplantation, Homologous