Evaluation of catheter-associated urinary tract infections and multi-drug-resistant Escherichia coli isolates from the urine of dogs with indwelling urinary catheters

J Am Vet Med Assoc. 2006 Nov 15;229(10):1584-90. doi: 10.2460/javma.229.10.1584.

Abstract

Objective: To determine the frequency of urinary tract infections (UTIs) in dogs with indwelling urinary catheters in an intensive care unit (ICU) and the frequency of multi-drug-resistant (MDR) Escherichia coli UTIs in those dogs.

Design: Prospective study.

Animals: All dogs in the ICU with an indwelling urinary catheter from January 2003 through December 2003.

Procedures: Urine samples and rectal swab specimens were collected at admission and every 3 days until discharge from the hospital. Escherichia coli isolates from urine samples and rectal swab specimens and those from dogs that were temporally or spatially associated with dogs with MDR E coli UTIs underwent antimicrobial susceptibility testing. Pulsed-field gel electrophoresis was performed on MDR isolates from urine and rectal swab specimens.

Results: Urinary catheters were placed in 137 dogs. Twenty-six UTIs were diagnosed, 15 on the day of admission and 11 after 3 or more days of catheterization. Of 12 dogs with E coli UTIs, 6 were infected at admission and 6 acquired the infection in the ICU. Two MDR E coli UTIs were detected, 1 of which was acquired in the ICU. One MDR E coli urinary isolate had an electrophoresis pattern similar to that of rectal isolates from the same dog. Urinary E coli isolates were most frequently resistant to ampicillin and cephalothin.

Conclusions and clinical relevance: The ICU-acquired MDR E coli UTI likely originated from the dog's intestinal flora during hospitalization. Dogs that have been referred from a community practice may have MDR E coli UTIs at the time of admission.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology*
  • Catheters, Indwelling / adverse effects*
  • Colony Count, Microbial
  • Cross Infection / veterinary
  • Dog Diseases / drug therapy
  • Dog Diseases / etiology
  • Dog Diseases / microbiology*
  • Dogs
  • Drug Resistance, Bacterial*
  • Drug Resistance, Multiple, Bacterial
  • Escherichia coli / drug effects*
  • Escherichia coli Infections / drug therapy
  • Escherichia coli Infections / etiology
  • Escherichia coli Infections / microbiology
  • Escherichia coli Infections / veterinary*
  • Female
  • Hospitalization
  • Male
  • Microbial Sensitivity Tests / veterinary
  • Prospective Studies
  • Rectum / microbiology
  • Urinary Tract Infections / drug therapy
  • Urinary Tract Infections / etiology
  • Urinary Tract Infections / microbiology
  • Urinary Tract Infections / veterinary*
  • Urine / microbiology

Substances

  • Anti-Bacterial Agents