Myeloproliferative disease in the pathogenesis and survival of Budd-Chiari syndrome

Jasper H Smalberg; Sarwa Darwish Murad; Eric Braakman; Peter J Valk; Harry L A Janssen; Frank W G Leebeek

Myeloproliferative disease in the pathogenesis and survival of Budd-Chiari syndrome

Haematologica. 2006 Dec;91(12):1712-3.

Authors

Jasper H Smalberg, Sarwa Darwish Murad, Eric Braakman, Peter J Valk, Harry L A Janssen, Frank W G Leebeek

PMID: 17145613

Abstract

We studied the etiology, diagnosis and natural course of myeloproliferative disease (MPD) in 40 consecutive patients with Budd-Chiari syndrome (BCS). In 38% of the BCS patients with MPD another etiological factor was found. JAK2 mutation was present in 41% of the tested BCS patients. Survival was not significantly affected by the presence of MPD.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Budd-Chiari Syndrome / etiology*
Budd-Chiari Syndrome / mortality*
Female
Humans
Male
Middle Aged
Myeloproliferative Disorders / complications*
Myeloproliferative Disorders / mortality*
Survival Analysis