Lactic acid bacteria (LAB) bind to human B- or H-antigens expressed on intestinal mucosa

Hideaki Uchida; Yasushi Kawai; Hideki Kinoshita; Haruki Kitazawa; Koh Miura; Kenichi Shiiba; Akira Horii; Katsunori Kimura; Naoki Taketomo; Munehiro Oda; Takaji Yajima; Tadao Saito

doi:10.1271/bbb.60407

Lactic acid bacteria (LAB) bind to human B- or H-antigens expressed on intestinal mucosa

Biosci Biotechnol Biochem. 2006 Dec;70(12):3073-6. doi: 10.1271/bbb.60407. Epub 2006 Dec 7.

Authors

Hideaki Uchida¹, Yasushi Kawai, Hideki Kinoshita, Haruki Kitazawa, Koh Miura, Kenichi Shiiba, Akira Horii, Katsunori Kimura, Naoki Taketomo, Munehiro Oda, Takaji Yajima, Tadao Saito

Affiliation

¹ Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University. hideaki7@bios.tohoku.ac.jp

PMID: 17151450
DOI: 10.1271/bbb.60407

Abstract

Twenty lactobacilli isolated from human feces were studied for binding to the human blood type B-antigen [Galalpha1-3 (Fucalpha1-2) Gal-] and H-antigen (Fucalpha1-2Gal-] expressed sugar chains in human intestinal mucosa. We found two strains, L. gasseri OLL2755 and L. gasseri OLL2877 that firmly adhere to human B-antigen, and we found L. gasseri OLL2827 bound to the H-antigen.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacterial Adhesion*
Blood Group Antigens / immunology*
Humans
Intestinal Mucosa / immunology*
Lactobacillus / physiology*

Substances

Blood Group Antigens