Na(+) and flagella-dependent swimming of alkaliphilic Bacillus pseudofirmus OF4: a basis for poor motility at low pH and enhancement in viscous media in an "up-motile" variant

Arch Microbiol. 2007 Mar;187(3):239-47. doi: 10.1007/s00203-006-0192-7. Epub 2006 Dec 13.

Abstract

Flagella-based motility of extremely alkaliphilic Bacillus species is completely dependent upon Na(+). Little motility is observed at pH values < approximately 8.0. Here we examine the number of flagella/cell as a function of growth pH in the facultative alkaliphile Bacillus pseudofirmus OF4 and a derivative selected for increased motility on soft agar plates. Flagella were produced by both strains during growth in a pH range from 7.5 to 10.3. The number of flagella/cell and flagellin levels of cells were not strongly dependent on growth pH over this range in either strain although both of these parameters were higher in the up-motile strain. Assays of the swimming speed indicated no motility at pH < 8 with 10 mM Na(+), but significant motility at pH 7 at much higher Na(+) concentrations. At pH 8-10, the swimming speed increased with the increase of Na(+) concentration up to 230 mM, with fastest swimming at pH 10. Motility of the up-motile strain was greatly increased relative to wild-type on soft agar at alkaline pH but not in liquid except when polyvinylpyrrolidone was added to increase viscosity. The up-motile phenotype, with increased flagella/cell may support bundle formation that particularly enhances motility under a subset of conditions with specific challenges.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkalies / pharmacology*
  • Bacillus / drug effects*
  • Bacillus / genetics
  • Bacillus / growth & development
  • Bacillus / physiology*
  • Cell Movement
  • Chemotaxis*
  • Culture Media
  • Flagella / physiology*
  • Flagellin / genetics*
  • Flagellin / metabolism
  • Gene Expression Regulation, Bacterial
  • Genes, Bacterial
  • Hydrogen-Ion Concentration
  • Repressor Proteins
  • Viscosity

Substances

  • Alkalies
  • Culture Media
  • Repressor Proteins
  • Flagellin