Diversely substituted sugar-linked alpha,beta-unsaturated gamma-lactones from sugar-derived Baylis-Hillman adducts via a RCM

Palakodety Radha Krishna; M Narsingam

doi:10.1021/cc060076c

Diversely substituted sugar-linked alpha,beta-unsaturated gamma-lactones from sugar-derived Baylis-Hillman adducts via a RCM

J Comb Chem. 2007 Jan-Feb;9(1):62-9. doi: 10.1021/cc060076c.

Authors

Palakodety Radha Krishna¹, M Narsingam

Affiliation

¹ D-206/B, Discovery Laboratory, Organic Chemistry Division III, Indian Institute of Chemical Technology, Hyderabad-500 007, India. prkgenius@iict.res.in

PMID: 17206833
DOI: 10.1021/cc060076c

Abstract

A versatile protocol for the production of sugar-linked alpha,beta-unsaturated gamma-lactones with stereochemical and functional group diversity is described starting from sugar-derived Baylis-Hillman adducts via ring-closing metathesis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkenes / chemical synthesis*
Alkenes / chemistry
Carbohydrates / chemical synthesis*
Carbohydrates / chemistry
Combinatorial Chemistry Techniques / methods
Lactones / chemical synthesis*
Lactones / chemistry
Magnetic Resonance Spectroscopy
Molecular Structure
Optical Rotation
Spectrometry, Mass, Electrospray Ionization
Spectrophotometry, Infrared
Stereoisomerism

Substances

Alkenes
Carbohydrates
Lactones