Early risk factors, job strain, and atherosclerosis among men in their 30s: the Cardiovascular Risk in Young Finns Study

Am J Public Health. 2007 Mar;97(3):450-2. doi: 10.2105/AJPH.2005.078873. Epub 2007 Jan 31.

Abstract

We examined whether preemployment influences confounded the association between job strain and atherosclerosis. We assessed biological, familial, and socioeconomic risk factors of coronary heart disease at 12 to 18 years of age and job strain and carotid artery intima-media thickness at 33 to 39 years of age for a cohort of 358 men. Adolescent risk factors predicted adult intima-media thickness but had little effect on the dose-response relation between greater job strain and greater intima-media thickness. Pre-employment influences did not confound the association between job strain and atherosclerosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Atherosclerosis / economics
  • Atherosclerosis / epidemiology*
  • Atherosclerosis / psychology
  • Biomarkers
  • Blood Pressure
  • Body Mass Index
  • Carotid Arteries / diagnostic imaging
  • Carotid Arteries / pathology*
  • Child
  • Cholesterol / blood
  • Employment / psychology*
  • Finland / epidemiology
  • Humans
  • Longitudinal Studies
  • Male
  • Occupational Diseases / economics
  • Occupational Diseases / epidemiology*
  • Occupational Diseases / psychology
  • Risk Assessment
  • Risk Factors
  • Smoking
  • Socioeconomic Factors
  • Stress, Psychological / complications*
  • Stress, Psychological / pathology
  • Tunica Intima / diagnostic imaging
  • Tunica Intima / pathology*
  • Ultrasonography

Substances

  • Biomarkers
  • Cholesterol