A needle-type multi-electrode array for the hypodermic continuous glucose monitoring sensor was fabricated using MEMS technology. The developed multielectrode sensor has 4 electrodes of two working(Pt) electrodes, one counter(Pt) electrode, and one reference(Ag/AgCl) electrode. Two working electrodes are for the enzyme and nonenzyme electrodes which measure glucose concentration and the background current (I(0)), respectively. The developed integrated sensor system is adequate to accomplish our prereported new two-point calibration method using only one-point sample measurement. Results of in vitro performance test are also provided.