Undiagnosed medulloblastoma presenting as fatal hemorrhage in a 14-year-old boy: case report and review of the literature

Childs Nerv Syst. 2007 Jul;23(7):799-805. doi: 10.1007/s00381-006-0290-5. Epub 2007 Feb 6.

Abstract

Introduction: A 14-year-old boy with no significant medical history presented to the emergency room with a sudden onset of severe headache of 1 day's duration. On admission, a non-contrast computed tomography (CT) of the head showed a posterior fossa hemorrhagic mass.

Materials and methods: He was immediately intubated and underwent placement of an external drainage tube. A magnetic resonance imaging (MRI) was performed, which showed a large hemorrhagic mass with upward cerebellar herniation.

Results: Despite aggressive measures, he deteriorated and was pronounced brain dead 2 days after admission. Pathological examination of the mass revealed a medulloblastoma with extensive neuronal and astrocytic differentiation.

Conclusion: This case represents one of the few cases of rapid, hemorrhagic expansion associated with a previously undiagnosed medulloblastoma. The topic of hemorrhage due to previously unrecognized brain tumors is discussed and the value of imaging methods used in the diagnostic assessment is emphasized.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Brain Neoplasms / complications*
  • Brain Neoplasms / pathology
  • Cerebral Hemorrhage / etiology*
  • Cerebral Hemorrhage / pathology
  • Cerebral Hemorrhage / surgery
  • Fatal Outcome
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Medulloblastoma / complications*
  • Medulloblastoma / pathology
  • Tomography, X-Ray Computed