Polymeric model systems for flavoenzyme activity: towards synthetic flavoenzymes

Chem Commun (Camb). 2007 Mar 28:(12):1248-50. doi: 10.1039/b616159f. Epub 2006 Dec 18.

Abstract

We report the synthesis of a water-soluble flavin polymer using ATRP, whereby the oligoethylene glycol backbone provides both a local hydrophobic environment and redox tuning of the flavin moiety typical of flavoenzyme prototypes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Enzymes / chemistry*
  • Flavins / chemistry*
  • Models, Molecular*
  • Protein Conformation
  • Spectrophotometry, Ultraviolet

Substances

  • Enzymes
  • Flavins