Sleep apnoea in heart failure

Eur Respir J. 2007 Jun;29(6):1201-5. doi: 10.1183/09031936.00037106. Epub 2007 Mar 14.

Abstract

Studies from the USA have reported that sleep apnoea is common in congestive heart failure (CHF), with Cheyne-Stokes respiration (CSR) being the most frequent type of sleep-disordered breathing (SDB) in these patients. Within the present study, the authors sought to assess the prevalence and type of SDB among CHF patients in Germany. A total of 203 CHF patients participated in this prospective multicentre study. All patients were stable in New York Heart Association classes II and III and had a left ventricular ejection fraction (LVEF)<40%. The patients were investigated by polygraphy and all data were centrally analysed. Patient enrolment was irrespective of sleep-related symptoms. The majority of patients were male with a mean age of 65 yrs and hospitalised. Of the 203 patients, 145 (71%) had an apnoea/hypopnoea index>10.h(-1), obstructive sleep apnoea (OSA) occurred in 43% (n=88) and CSR in 28% (n=57) of patients. The prevalence of sleep-disordered breathing is high in patients with stable severe congestive heart failure from a European population. As sleep-disordered breathing may have a negative impact on the prognosis of congestive heart failure, a sleep study should be performed in every patient with congestive heart failure and a left ventricular ejection fraction of <40%. This diagnostic approach should probably be adopted for all of these patients irrespective of the presence of sleep-related symptoms.

MeSH terms

  • Aged
  • Cheyne-Stokes Respiration
  • Continuous Positive Airway Pressure
  • Female
  • Heart Failure / complications*
  • Heart Failure / diagnosis*
  • Heart Failure / pathology*
  • Humans
  • Male
  • Middle Aged
  • Oxygen Inhalation Therapy
  • Polysomnography / methods
  • Pressure
  • Respiration
  • Sleep
  • Sleep Apnea Syndromes / complications*
  • Sleep Apnea, Obstructive / diagnosis