Successful treatment of severe refractory atopic dermatitis with efalizumab

J Drugs Dermatol. 2006 Nov-Dec;5(10):994-8.

Abstract

Despite multiple therapeutic modalities, treatment of atopic dermatitis with its chronic, relapsing nature remains a challenge. Chronic use of standard therapies is associated with variable efficacy and potential side effects. Targeted therapeutic approaches using biologic agents may prove to be a novel alternative. We present a case of severe recalcitrant atopic dermatitis successfully treated with efalizumab.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antibodies, Monoclonal / immunology
  • Antibodies, Monoclonal / pharmacology
  • Antibodies, Monoclonal / therapeutic use*
  • Antibodies, Monoclonal, Humanized
  • CD11 Antigens / immunology
  • Dermatitis, Atopic / drug therapy*
  • Dermatitis, Atopic / immunology
  • Drug Resistance
  • Female
  • Follow-Up Studies
  • Humans
  • Treatment Outcome

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • CD11 Antigens
  • efalizumab