Abstract
The amelogenin protein is considered as the major molecular marker of developing ectodermal enamel. Recent data suggest other roles for amelogenin beyond structural regulation of enamel mineral crystal growth. Here we describe our novel discovery of amelogenin expression in long bone cells, in cartilage cells, in cells of the epiphyseal growth plate, and in bone marrow stromal cells.
(c) 2007 Wiley-Liss, Inc.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amelogenin / analysis*
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Amelogenin / chemistry
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Amelogenin / genetics
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Amino Acid Sequence
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Animals
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Bone Marrow Cells / chemistry*
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Cartilage / chemistry*
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Cartilage / cytology
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Cells, Cultured
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Dogs
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Femur / chemistry*
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Femur / cytology
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Gene Expression
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Growth Plate / chemistry*
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Growth Plate / cytology
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Immunohistochemistry
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In Situ Hybridization
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Male
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Mesenchymal Stem Cells / chemistry*
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Microscopy, Confocal
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Molecular Sequence Data
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Osteoblasts / chemistry
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Osteoclasts / chemistry
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Osteocytes / chemistry
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RNA, Messenger / analysis
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Rats
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Sequence Analysis, Protein
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Stromal Cells / chemistry
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Tibia / chemistry*
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Tibia / cytology
Substances
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Amelogenin
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RNA, Messenger