Localization, quantification, and characterization of tuftelin in soft tissues

Anat Rec (Hoboken). 2007 May;290(5):449-54. doi: 10.1002/ar.20512.

Abstract

Tuftelin was initially found in the developing and mature extracellular enamel. Here we describe our novel discovery of tuftelin cellular distribution (protein and mRNA) in six soft tissues. The expression levels of tuftelin mRNA were significantly higher in mouse kidney and testis, in which oxygen levels are hovering closely to hypoxia under normal conditions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blotting, Western
  • Brain Chemistry
  • Cell Hypoxia
  • Dental Enamel Proteins / analysis*
  • Dental Enamel Proteins / genetics
  • Eye / chemistry
  • Gene Expression*
  • Immunohistochemistry
  • In Situ Hybridization
  • Kidney / chemistry*
  • Kidney / physiology
  • Liver / chemistry
  • Lung / chemistry
  • Male
  • Mice
  • Mice, Inbred BALB C
  • Microscopy, Confocal
  • RNA, Messenger / analysis
  • Reverse Transcriptase Polymerase Chain Reaction
  • Testis / chemistry*
  • Testis / physiology
  • Up-Regulation

Substances

  • Dental Enamel Proteins
  • RNA, Messenger
  • tuftelin