Abstract
The catabolic pathway for flavodoxin has yet to be clarified for any bacterial species. In this study, we found that the flavin mononucleotide in the flavodoxin of Helicobacter pylori is degraded to riboflavin via the phosphomonoesterase activity of class C acid phosphatase. The result is a conversion of holoflavodoxin to apoflavodoxin.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Apoproteins / chemistry
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Apoproteins / metabolism*
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Bacterial Proteins / chemistry
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Bacterial Proteins / metabolism
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Flavin Mononucleotide / chemistry
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Flavin Mononucleotide / metabolism
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Flavodoxin / chemistry
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Flavodoxin / metabolism*
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Helicobacter pylori / growth & development
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Helicobacter pylori / metabolism*
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Holoenzymes / chemistry
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Holoenzymes / metabolism*
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Phosphorylation
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Riboflavin / chemistry
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Riboflavin / metabolism
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Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Substances
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Apoproteins
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Bacterial Proteins
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Flavodoxin
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Holoenzymes
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apoflavodoxin
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Flavin Mononucleotide
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Riboflavin