Effect of renal insufficiency on the pharmacokinetics of sitagliptin, a dipeptidyl peptidase-4 inhibitor

Diabetes Care. 2007 Jul;30(7):1862-4. doi: 10.2337/dc06-2545. Epub 2007 Apr 27.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Enzyme Inhibitors / pharmacokinetics
  • Female
  • Humans
  • Hypoglycemic Agents / pharmacokinetics*
  • Male
  • Middle Aged
  • Pyrazines / pharmacokinetics*
  • Renal Insufficiency / etiology
  • Renal Insufficiency / physiopathology*
  • Sitagliptin Phosphate
  • Triazoles / pharmacokinetics*

Substances

  • Enzyme Inhibitors
  • Hypoglycemic Agents
  • Pyrazines
  • Triazoles
  • Sitagliptin Phosphate