Morphological and functional changes of cardiovascular system in postmenopausal women

Eur Rev Med Pharmacol Sci. 2007 Mar-Apr;11(2):107-17.

Abstract

Background: The incidence of cardiovascular events in reproductive age women is 3 times lower than in men, whereas this ratio noticeably changes on menopausal beginning. Postmenopausal women are more exposed to the effects of risk factors, which are present in a noticeably different entity in physiological or surgical menopause; and in the latter whether on substitutive hormonal treatment or not.

Methods: This study, carried out in Rome and Latina, has involved 743 postmenopausal women, of whom 545 with physiological menopause and 198 with iatrogenic menopause.

Results: The average blood pressure value as well as the incidence of hypertension, hypercholesterolemia, diabetes mellitus, obesity and smoking have a significantly different trend in physiological versus iatrogenic postmenopausal women; and in the latter whether on substitutive hormonal treatment or not.

Conclusions: Studying life-style and evaluating risk factors in postmenopausal women, and giving an up-to-date view about the prevalence oh health conditions at risk, will allow us to promote both primary and secondary prevention actions.

Publication types

  • Multicenter Study

MeSH terms

  • Age Distribution
  • Age Factors
  • Aged
  • Blood Pressure
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / etiology*
  • Cardiovascular Diseases / physiopathology
  • Cardiovascular System / physiopathology*
  • Diabetes Mellitus / epidemiology
  • Diabetes Mellitus / physiopathology
  • Female
  • Hormone Replacement Therapy / adverse effects
  • Humans
  • Hypercholesterolemia / complications
  • Hypercholesterolemia / epidemiology
  • Hypercholesterolemia / physiopathology
  • Hypertension / complications
  • Hypertension / epidemiology
  • Hypertension / physiopathology
  • Incidence
  • Italy / epidemiology
  • Middle Aged
  • Obesity / complications
  • Obesity / epidemiology
  • Obesity / physiopathology
  • Postmenopause*
  • Prevalence
  • Risk Assessment
  • Risk Factors
  • Smoking / adverse effects
  • Smoking / epidemiology
  • Smoking / physiopathology