Antiphospholipid syndrome: a predisposing factor for early onset HELLP syndrome

Rheumatol Int. 2007 Dec;28(2):171-4. doi: 10.1007/s00296-007-0386-6. Epub 2007 Jun 19.

Abstract

Hemolysis elevated liver enzymes low platelets syndrome (HELLP) is a relatively rare pregnancy-related thrombotic microangiopathic disorder, usually observed during the third trimester. Its incidence seems to be increased in patients with antiphospholipid syndrome (APS). In this report, we describe a 33-year-old pregnant woman with previously known primary APS who developed early onset HELLP syndrome during the 15th week of gestation. We also review the literature about this interesting relationship between APS and HELLP.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abortion, Induced
  • Adult
  • Antiphospholipid Syndrome / complications*
  • Female
  • Genetic Predisposition to Disease*
  • Gestational Age
  • HELLP Syndrome / etiology*
  • Humans
  • Pregnancy
  • Pregnancy Complications, Hematologic / etiology*
  • Pregnancy Outcome
  • Pregnancy Trimester, Second