Emerging lupus-like manifestations in acute parvovirus B19 infection

Clin Rheumatol. 2008 Jan;27(1):119-20. doi: 10.1007/s10067-007-0691-1. Epub 2007 Jul 11.

Abstract

We encountered an adult patient with acute parvovirus B19 infection who presented with transient lupus-like symptoms (i.e., polyarthritis, fever, myalgia, pancytopenia, hypocomplementemia, and nephritis). Our case is characterized by the demonstration of acute nephritis as a complication of this infection, making it difficult to distinguish between a viral infection and the first episode of systemic lupus erythematosus.

Publication types

  • Case Reports

MeSH terms

  • Acetaminophen / therapeutic use
  • Acute Disease
  • Adult
  • Analgesics, Non-Narcotic / therapeutic use
  • Antibodies, Viral / analysis
  • Diagnosis, Differential
  • Female
  • Humans
  • Lupus Erythematosus, Systemic / diagnosis*
  • Lupus Erythematosus, Systemic / drug therapy
  • Lupus Erythematosus, Systemic / virology
  • Nephritis / diagnosis*
  • Nephritis / drug therapy
  • Nephritis / virology
  • Parvoviridae Infections / complications
  • Parvoviridae Infections / diagnosis*
  • Parvoviridae Infections / drug therapy
  • Parvovirus B19, Human / immunology
  • Parvovirus B19, Human / isolation & purification
  • Treatment Outcome

Substances

  • Analgesics, Non-Narcotic
  • Antibodies, Viral
  • Acetaminophen