The most common etiology of lymphedema in our environment is tumoral and, generally, it is due to treatment of the cancer itself. However, the initial presentation of prostate carcinoma as lymphedema is very rare. In fact, there aren't very few documented cases in literature. We described the case of a patient who was admitted into the hospital to be examined for lymphedema in his genitals and legs. Our patient was diagnosed of prostate carcinoma with retroperitoneal adenopathies. The best treatment in this case is block-hormonal therapy. Prognosis is very bad and the survival rate is poor within five years of diagnosis.