Optic disc size in a population-based study in central India: the Central India Eye and Medical Study (CIEMS)

Acta Ophthalmol. 2008 Feb;86(1):103-4. doi: 10.1111/j.1600-0420.2007.00964.x. Epub 2007 Jul 28.

Abstract

Purpose: To determine optic disc size and its associations in an adult population in central India.

Methods: The Central India Eye and Medical Study (CIEMS), Part 1 is a population-based, cross-sectional cohort study and included 1000 subjects out of 1314 (76.1%) subjects from a rural area of Maharasthra/India, aged 30+ years, invited to participate. Confocal laser scanning tomographic optic disc images were morphometrically examined.

Results: Mean optic disc area (2.25 +/- 0.51 mm2, range 1.12-4.61 mm2) was significantly correlated with myopic refractive error (p < 0.001) and axial length (p < 0.001), whereas gender (p = 0.14), body height (p = 0.44) and best corrected visual acuity (p = 0.59) were not significantly associated in multiple regression analysis.

Conclusions: Mean optic disc area is larger in the central Indian population than in White people. Axial length and myopic refractive error are independent factors that influence optic disc size.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Asian People*
  • Cohort Studies
  • Cross-Sectional Studies
  • Humans
  • India
  • Microscopy, Confocal
  • Middle Aged
  • Myopia / pathology*
  • Myopia / physiopathology*
  • Optic Disk / anatomy & histology*
  • Optic Disk / pathology*
  • Organ Size
  • Refraction, Ocular*