Surveillance following treatment for colorectal cancer in Australia. Has best practice been adopted by medical oncologists?

Intern Med J. 2008 Jun;38(6):415-21. doi: 10.1111/j.1445-5994.2007.01482.x.

Abstract

Background: Intensive follow up after surgery for colorectal cancer is associated with a significant survival advantage and is endorsed by expert panels, but are physicians convinced of the benefit?

Methods: A questionnaire was mailed to all members of the Medical Oncology Group of Australia, assessing surveillance practices after completion of adjuvant treatments.

Results: Responses were obtained from 141 (55%) medical oncologists of which 121 were considered evaluable. Thirteen per cent (n = 16) routinely did not carry out follow-up investigations. Of those carrying out surveillance, 47% (n = 51) nominated identifying potentially resectable metastatic disease as prime consideration. Many (44%) were motivated by patient reassurance and expectation. Carcinoembryonic antigen levels were commonly monitored 3 monthly in years 1 (77%, n = 85) and 2 (57%, n = 63) and 6 monthly thereafter (67%, n = 74). Eighty per cent (n = 88) carried out computed tomography (CT) surveillance 1 year after surgery, 69% (n = 76) at year 2 and 55% (n = 60) at year 3. Twenty-six per cent (n = 29) continued scanning annually up to 5 years. Inclusion of CT chest was routine for 33% (n = 36) and never carried out by 11% (n = 12).

Conclusion: A significant minority (13%) of oncologists carry out no follow-up investigations, despite level I evidence of a survival advantage similar to standard adjuvant therapies. Further education and study of physician attitudes and reservations to routine surveillance are required.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Australia / epidemiology
  • Biomarkers, Tumor / blood
  • Carcinoembryonic Antigen / blood
  • Clinical Competence*
  • Colorectal Neoplasms / diagnosis*
  • Colorectal Neoplasms / epidemiology
  • Colorectal Neoplasms / therapy
  • Combined Modality Therapy
  • Diagnostic Imaging / methods*
  • Humans
  • Medical Oncology / methods*
  • Morbidity
  • Population Surveillance / methods*
  • Prognosis
  • Retrospective Studies

Substances

  • Biomarkers, Tumor
  • Carcinoembryonic Antigen