Tête-à-tête: the function of FKBPs in plant development

Trends Plant Sci. 2007 Oct;12(10):465-73. doi: 10.1016/j.tplants.2007.08.015. Epub 2007 Sep 10.

Abstract

Compared with that of other eukaryotes, the nuclear genome of the model plant Arabidopsis thaliana encodes an expanded family of FK506-binding proteins (FKBPs). Whereas approximately half of the FKBPs are implicated in the regulation of photosynthetic processes, a subcluster appears to be stress responsive. Recent reports indicate that a discrete group of Arabidopsis multidomain FKBPs regulate plant hormone pathways by recruiting or modulating client proteins via direct protein-protein interactions (tête-à-tête). This suggests that multidomain FKBPs function as central elements in plant development by linking hormone responses with other signal transduction pathways. Here, we present a summary of current research demonstrating that, in addition to their role in protein folding, subsets of plant FKBPs exhibit diverse functionality.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Chloroplasts / metabolism
  • Photosynthesis
  • Plant Development*
  • Plant Growth Regulators / metabolism
  • Plants / genetics
  • Plants / metabolism*
  • Signal Transduction
  • Tacrolimus Binding Proteins / chemistry
  • Tacrolimus Binding Proteins / genetics
  • Tacrolimus Binding Proteins / metabolism*

Substances

  • Plant Growth Regulators
  • Tacrolimus Binding Proteins