Targeted degradation of the aryl hydrocarbon receptor by the PROTAC approach: a useful chemical genetic tool

Chembiochem. 2007 Nov 23;8(17):2058-62. doi: 10.1002/cbic.200700438.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chlorocebus aethiops
  • Molecular Structure
  • Protein Binding
  • Receptors, Aryl Hydrocarbon / chemistry*
  • Receptors, Aryl Hydrocarbon / genetics
  • Receptors, Aryl Hydrocarbon / metabolism*
  • Ubiquitin / metabolism
  • Ubiquitin-Protein Ligases / metabolism

Substances

  • Receptors, Aryl Hydrocarbon
  • Ubiquitin
  • Ubiquitin-Protein Ligases