An alkoxide-directed alkyne-allene cross-coupling for stereoselective synthesis of 1,4-dienes

Chem Commun (Camb). 2007 Nov 21:(43):4531-3. doi: 10.1039/b708256h. Epub 2007 Aug 23.

Abstract

A titanium alkoxide-mediated convergent coupling between internal alkynes and allenes is described for the regio- and stereocontrolled synthesis of substituted acyclic 1,4-dienes.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alcohols / chemical synthesis
  • Alcohols / chemistry*
  • Alkadienes / chemistry*
  • Alkynes / chemistry*
  • Polyenes / chemical synthesis*
  • Stereoisomerism
  • Titanium / chemistry

Substances

  • Alcohols
  • Alkadienes
  • Alkynes
  • Polyenes
  • propadiene
  • Titanium