Copper-catalyzed multicomponent reaction: facile access to functionalized 5-arylidene-2-imino-3-pyrrolines

Org Lett. 2007 Nov 22;9(24):5023-5. doi: 10.1021/ol702241e. Epub 2007 Nov 3.

Abstract

The synthesis of a novel class of 2-imino-5-arylidene-3-pyrrolines via a copper-catalyzed multicomponent reaction of sulfonyl azides with alkynes and aziridines is described. The protocol is efficient and general.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes / chemistry
  • Azides / chemistry
  • Catalysis
  • Copper / chemistry*
  • Iodides / chemistry*
  • Molecular Structure
  • Pyrroles / chemical synthesis*
  • Pyrroles / chemistry

Substances

  • Alkynes
  • Azides
  • Iodides
  • Pyrroles
  • pyrroline
  • Copper
  • cuprous iodide