Pharmacotherapy of cough-variant asthma

Expert Opin Pharmacother. 2007 Dec;8(17):3021-8. doi: 10.1517/14656566.8.17.3021.

Abstract

Cough-variant asthma is considered as an asthma subset in which chronic cough is the only symptom. It is believed to be more frequent and, hence, sometimes overdiagnosed in children, and shares with typical asthma eosinophilic airway inflammation and consequent bronchial hyper-responsiveness. Presently available therapies consist of bronchodilators, inhaled or oral corticosteroids, or leukotriene modifiers. However, the long-term efficacy of these agents in adults and children is not known. This review focuses on current therapies used for cough variant asthma, also highlighting potential therapeutic targets for this condition.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Anti-Asthmatic Agents / therapeutic use*
  • Asthma / classification
  • Asthma / complications
  • Asthma / drug therapy*
  • Asthma / pathology
  • Asthma / physiopathology
  • Bronchial Hyperreactivity / drug therapy
  • Bronchodilator Agents / therapeutic use
  • Cough / drug therapy
  • Cough / etiology*
  • Cough / pathology
  • Cough / physiopathology
  • Eosinophils / pathology
  • Humans
  • Leukotriene Antagonists / therapeutic use
  • Treatment Outcome

Substances

  • Adrenal Cortex Hormones
  • Anti-Asthmatic Agents
  • Bronchodilator Agents
  • Leukotriene Antagonists