Prospective study demonstrating the efficacy of combined preoperative three-day application of antibiotics and povidone-iodine irrigation

Ann Ophthalmol (Skokie). 2007 Winter;39(4):313-7. doi: 10.1007/s12009-007-9007-y.

Abstract

In 50 patients undergoing anterior segment intraocular surgery we determined that a three-day course of topical ofloxacin followed by preoperative povidone-iodine irrigation caused a marked decrease in the number of conjunctival bacterial flora and resulted in no contamination of the anterior chamber aqueous fluid at the beginning and conclusion of surgery.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Topical
  • Anterior Eye Segment / surgery*
  • Anti-Bacterial Agents / administration & dosage*
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Infective Agents, Local / administration & dosage*
  • Anti-Infective Agents, Local / therapeutic use
  • Aqueous Humor / microbiology
  • Bacteria / isolation & purification
  • Conjunctiva / microbiology
  • Drug Administration Schedule
  • Humans
  • Ofloxacin / administration & dosage*
  • Ofloxacin / therapeutic use
  • Ophthalmologic Surgical Procedures*
  • Postoperative Period
  • Povidone-Iodine / administration & dosage*
  • Povidone-Iodine / therapeutic use
  • Preoperative Care*
  • Prospective Studies
  • Therapeutic Irrigation
  • Time Factors
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents, Local
  • Povidone-Iodine
  • Ofloxacin