Solitary fibrous tumor in the cervical spine with destructive vertebral involvement: a case report and review of the literature

Arch Orthop Trauma Surg. 2008 Oct;128(10):1111-6. doi: 10.1007/s00402-007-0529-y. Epub 2007 Dec 4.

Abstract

Introduction: Recently, solitary fibrous tumors occurring in spine-related lesions have been reported. However, the destruction of vertebral bodies by this type of tumor has not been reported.

Materials and methods: A 71-year-old female presented with pain from a mass on the right side of her neck. Plain radiographs of the cervical spine showed collapse of the C5 vertebral body and dislocation of the C4 vertebral body. The MRI image showed a large mass surrounding C4 and C5, which had low signal intensity in the T1W image and high signal intensity in the T2W image. At first, resection of the tumor and spinal fusion was performed by anterior approach.

Results: Histology revealed a solitary fibrous tumor with proliferating spindle cells. Immunohistochemistry showed positive stains for vimentin and CD34. One year postoperatively, a local recurrence manifested extensive destruction of the C4 and C5 vertebral bodies. Then, palliative surgery with posterior cervical instrumentation and radiation therapy were performed. Because the destruction proceeded and the rods were broken 2 years after, she underwent additional occipito-cervical instrumentation.

Conclusions: This is the first report of a solitary fibrous tumor that involves the destruction of the spinal structure. An extensive destruction of the vertebral body by the solitary fibrous tumor needs to be aware in treating this tumor with spinal involvement.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Cervical Vertebrae / pathology*
  • Female
  • Humans
  • Radiography
  • Reoperation
  • Solitary Fibrous Tumors / complications*
  • Solitary Fibrous Tumors / diagnostic imaging
  • Solitary Fibrous Tumors / surgery
  • Spinal Neoplasms / complications*
  • Spinal Neoplasms / diagnostic imaging
  • Spinal Neoplasms / surgery
  • Treatment Outcome