Intracranial hypotension from intrathecal baclofen pump insertion. A case report and review of the literature

Stereotact Funct Neurosurg. 2008;86(2):75-9. doi: 10.1159/000112427. Epub 2007 Dec 12.

Abstract

Intracranial hypotension is a syndrome of low cerebrospinal fluid pressure with a variable clinical presentation ranging from postural headaches to coma. A number of neuroradiologic techniques are now available to aid in the diagnosis of this syndrome (CT, MRI, radioisotope cisternography and CT myelography), each showing specific radiographic abnormalities. In this report, we present a case of intracranial hypotension secondary to baclofen pump placement. We review the major clinical findings, neuroimaging abnormalities, key diagnostic features as well as treatment options.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Baclofen / administration & dosage*
  • Baclofen / therapeutic use
  • Cerebrospinal Fluid Pressure / physiology
  • Female
  • Humans
  • Infusion Pumps, Implantable / adverse effects*
  • Intracranial Hypotension / diagnosis
  • Intracranial Hypotension / etiology*
  • Intracranial Hypotension / physiopathology
  • Middle Aged
  • Muscle Relaxants, Central / administration & dosage*
  • Muscle Relaxants, Central / therapeutic use
  • Muscle Spasticity / drug therapy
  • Tomography, X-Ray Computed

Substances

  • Muscle Relaxants, Central
  • Baclofen