Nowadays, computed tomography (CT) is established for diagnosing gastrointestinal bleeding. In this retrospective study, the use of CT in diagnosing gastrointestinal bleeding was evaluated. Fifty-three patients received a contrast-medium-enhanced helical multislice CT (MSCT) to locate the bleeding site. Seventy-nine percent of the hemorrhage were acute gastrointestinal bleedings. Fifty-five percent of the acute hemorrhages were located via helical MSCT, 45% of the chronic bleeding sites were detected. Notably, bleeding of diverticula, tumors, and angiodysplasias were well demonstrated. In conclusion, contrast-medium-enhanced MSCT may be used effectively as a noninvasive diagnostic tool for detecting gastrointestinal bleedings.