Early sequential development of infective dermatitis, human T cell lymphotropic virus type 1-associated myelopathy, and adult T cell leukemia/lymphoma

Clin Infect Dis. 2008 Feb 1;46(3):440-2. doi: 10.1086/524695.

Abstract

We describe a patient with human T cell lymphotropic virus type 1 (HTLV-1)-associated infective dermatitis who developed HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T cell leukemia/lymphoma at 16 years of age. Long inverse polymerase chain reaction was used to demonstrate monoclonal integration of proviral DNA in the lymphomatous skin lesion.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Dermatitis / cerebrospinal fluid
  • Dermatitis / virology*
  • Female
  • HTLV-I Antibodies / cerebrospinal fluid
  • Human T-lymphotropic virus 1 / immunology
  • Human T-lymphotropic virus 1 / isolation & purification*
  • Humans
  • Leukemia-Lymphoma, Adult T-Cell / cerebrospinal fluid
  • Leukemia-Lymphoma, Adult T-Cell / virology*
  • Paraparesis, Tropical Spastic / cerebrospinal fluid
  • Paraparesis, Tropical Spastic / virology*
  • Polymerase Chain Reaction

Substances

  • HTLV-I Antibodies