Behçet's disease complicated by IgA nephropathy with nephrotic syndrome

Clin Exp Nephrol. 2008 Jun;12(3):224-7. doi: 10.1007/s10157-008-0029-6. Epub 2008 Jan 26.

Abstract

A 65-year-old woman with a 48-year history of Behçet's disease associated with nephrotic syndrome is described. Immunofluorescence study revealed IgA nephropathy. Following treatment with an angiotensin II type-I receptor-blocker, an anti-platelet drug, and an HMG-CoA reductase inhibitor, accompanied by dietary restrictions of protein and sodium, proteinuria was markedly decreased. This report describes our experience with a rare entity of Behçet's disease complicated by nephrotic syndrome due to IgA nephropathy. Routine urine examination and renal biopsy are needed for the detection and diagnosis of renal problems with Behçet's disease.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angiotensin II Type 1 Receptor Blockers / therapeutic use
  • Atorvastatin
  • Behcet Syndrome / complications*
  • Behcet Syndrome / diagnosis*
  • Behcet Syndrome / drug therapy
  • Benzimidazoles / therapeutic use
  • Biphenyl Compounds / therapeutic use
  • Dilazep / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Glomerulonephritis, IGA / complications*
  • Heptanoic Acids / therapeutic use
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
  • Nephrotic Syndrome / complications*
  • Nephrotic Syndrome / diagnosis*
  • Nephrotic Syndrome / etiology
  • Pyrroles / therapeutic use
  • Tetrazoles / therapeutic use
  • Vasodilator Agents / therapeutic use

Substances

  • Angiotensin II Type 1 Receptor Blockers
  • Benzimidazoles
  • Biphenyl Compounds
  • Heptanoic Acids
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Pyrroles
  • Tetrazoles
  • Vasodilator Agents
  • Atorvastatin
  • Dilazep
  • candesartan cilexetil