Radiofrequency ablation for the treatment of renal cell carcinoma: initial experience

Radiat Med. 2008 Jan;26(1):1-5. doi: 10.1007/s11604-007-0183-x. Epub 2008 Jan 31.

Abstract

Purpose: The aim of this retrospective study was to evaluate the clinical value of percutaneous radiofrequency ablation (RFA) for the treatment of renal cell carcinoma (RCC).

Materials and methods: In a recent 3 years seven RCCs in six patients were treated by percutaneous RFA. RCC had been diagnosed based on the typical findings by computed tomography and/or magnetic resonance imaging. A cool-tip RF system (Vallylab) was mainly used with a RF2000 generator. The maximum tumor size ranged from 8 to 40 mm in diameter. The follow-up period was 14-36 months after initial RFA treatment.

Results: Complete disappearance of contrast enhancement during the early arterial phase was noted immediately after each session of percutaneous RFA. Two RCCs > or = 3 cm in diameter showed tumor recurrence and required re-RFA during the follow-up period. In one patient, retroperitoneal hematoma was observed as a noteworthy complication.

Conclusion: Despite our limited number of patients, we believe that percutaneous RFA is clinically feasible and can be an alternative treatment of choice for RCC.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Carcinoma, Renal Cell / surgery*
  • Catheter Ablation*
  • Female
  • Humans
  • Kidney Neoplasms / surgery*
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Retrospective Studies
  • Tomography, X-Ray Computed
  • Treatment Outcome