A new phenolic amide from the roots of Paris verticillata

Molecules. 2008 Jan 16;13(1):41-5. doi: 10.3390/molecules13010041.

Abstract

A new phenolic amide 8, together with the nine known phenolic compounds 1-7, 9 and 10 were isolated from the MeOH extract of the roots of Paris verticillata. The structure of the new compound 8 was determined to be 1-N-feruloylaminobutyl-4-rho-hydroxybenzamide by spectroscopic methods. The isolated compounds were tested for cytotoxicity against four human tumor cell lines using the SRB assay.

MeSH terms

  • Amides / chemistry
  • Amides / isolation & purification*
  • Amides / pharmacology*
  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Cell Death / drug effects
  • Cell Line, Tumor
  • Drug Screening Assays, Antitumor
  • Humans
  • Liliaceae / chemistry*
  • Liliaceae / drug effects
  • Magnetic Resonance Spectroscopy
  • Phenols / chemistry
  • Phenols / isolation & purification*
  • Phenols / pharmacology*
  • Plant Roots / chemistry*
  • Plant Roots / drug effects

Substances

  • Amides
  • Antineoplastic Agents, Phytogenic
  • Phenols