Abstract
A new phenolic amide 8, together with the nine known phenolic compounds 1-7, 9 and 10 were isolated from the MeOH extract of the roots of Paris verticillata. The structure of the new compound 8 was determined to be 1-N-feruloylaminobutyl-4-rho-hydroxybenzamide by spectroscopic methods. The isolated compounds were tested for cytotoxicity against four human tumor cell lines using the SRB assay.
MeSH terms
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Amides / chemistry
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Amides / isolation & purification*
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Amides / pharmacology*
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification
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Antineoplastic Agents, Phytogenic / pharmacology
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Cell Death / drug effects
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Cell Line, Tumor
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Drug Screening Assays, Antitumor
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Humans
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Liliaceae / chemistry*
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Liliaceae / drug effects
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Magnetic Resonance Spectroscopy
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Phenols / chemistry
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Phenols / isolation & purification*
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Phenols / pharmacology*
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Plant Roots / chemistry*
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Plant Roots / drug effects
Substances
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Amides
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Antineoplastic Agents, Phytogenic
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Phenols