Abstract
ABCG2, a transporter of the ATP-binding cassette family, is known to play a prominent role in the absorption, distribution, metabolism, and excretion of xenobiotics. Drug-transporter interactions are commonly screened by in vitro systems using transfected insect and/or human cell lines.
MeSH terms
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ATP Binding Cassette Transporter, Subfamily G, Member 2
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ATP-Binding Cassette Transporters / drug effects
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ATP-Binding Cassette Transporters / metabolism*
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Animals
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Biological Transport
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Cell Line
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Drug Interactions
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Drug Therapy
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Humans
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Insecta
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Neoplasm Proteins / drug effects
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Neoplasm Proteins / metabolism*
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Xenobiotics / pharmacokinetics
Substances
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ABCG2 protein, human
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ATP Binding Cassette Transporter, Subfamily G, Member 2
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ATP-Binding Cassette Transporters
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Neoplasm Proteins
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Xenobiotics