The Mini Mental State Examination (MMSE) is used widely internationally. Data on population age and gender distribution of MMSE scores outside of the US is rare. The Composite International Diagnostic Interview (CIDI), which incorporates the MMSE, was administered to a household sample of 2978 individuals age 15 and older in Chile. DSM-III-R lifetime prevalence rates were estimated. The average MMSE score ranged from 16-29 depending on the level of educational attainment. Sociodemographic variables, including age marital status, urban-rural and income, impacted MMSE scores. When the MMSE scores were controlled for sociodemographic variables, those with any psychiatric disorder had significantly lower scores; however, specific diagnoses did not affect MMSE scores.