Abstract
Apolipoprotein mimetic peptides have been shown to dramatically reduce atherosclerosis in animal models. Atherosclerosis is an example of an inflammatory disorder. Published studies of apolipoprotein mimetic peptides in models of inflammatory disorders other than atherosclerosis suggest that they may have efficacy in a wide range of inflammatory conditions.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Apolipoprotein A-I / physiology
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Apolipoprotein A-I / therapeutic use*
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Apolipoproteins / physiology*
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Apolipoproteins / therapeutic use
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Atherosclerosis / physiopathology*
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Diabetes Mellitus, Experimental / physiopathology
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Humans
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Infections
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Inflammation / physiopathology*
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Molecular Mimicry
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Peptides / physiology
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Vascular Diseases / physiopathology
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Vascular Diseases / therapy
Substances
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Apolipoprotein A-I
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Apolipoproteins
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D-4F peptide
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Peptides