[Inhibit affection of resveratrol on the growth of Hep-2 cell line]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2007 Dec;21(24):1129-31.
[Article in Chinese]

Abstract

Objective: To study the inhibitory effect of resveratrol on growth of human laryngeal cancer cell line, Hep-2.

Method: Count cell number under microscope, MTT assay was used to determine the cell growth inhibitory rate. Soft agar colony forming experiment was performed to observe the proliferation ability, before or after resveratrol treatment.

Result: Resveratrol was able to depress cell growth and inhibit cell proliferation.

Conclusion: Resveratrol strongly inhibit Hep-2 cell proliferation in a time- and dose-dependent manner.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Cycle / drug effects
  • Cell Line, Tumor
  • Cell Proliferation / drug effects*
  • Dose-Response Relationship, Drug
  • Humans
  • Resveratrol
  • Stilbenes / pharmacology*

Substances

  • Stilbenes
  • Resveratrol