Spatiotemporal patterns of oscillatory brain activity during auditory word recognition in children: a synthetic aperture magnetometry study

Int J Psychophysiol. 2008 May;68(2):141-8. doi: 10.1016/j.ijpsycho.2007.11.005. Epub 2008 Feb 8.

Abstract

Objective: We studied the task-induced spatiotemporal evolution and characteristics of cortical neural oscillations in children during an auditory word recognition task.

Methods: We presented abstract nouns binaurally and recorded the MEG response in eight healthy right-handed children (6-12 years). We calculated the event-related changes in cortical oscillations using a beamformer spatial filter analysis technique (SAM), then transformed each subject's statistical maps into standard space and used these to make group statistical inferences.

Results: Across subjects, the cortical response to words could be divided into at least two phases: an initial event-related synchronization in both the right temporal (100-300 ms, 15-25 Hz; 200-400 ms, 5-15 Hz) and left frontal regions (200-400 ms; 15-25 Hz); followed by a strong left-lateralized event-related desynchronization in the left temporal region (500-700 ms; 5-15 Hz).

Conclusions: We found bilateral event-related synchronization followed by later left lateralized event-related desynchronization in language-related cortical areas. These data demonstrate the spatiotemporal time course of neural activation during an auditory word recognition task in a group of children. As well, this demonstrates the utility of SAM analyses to detect subtle sequential task-related neural activations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Auditory Perception / physiology*
  • Brain Mapping*
  • Cerebral Cortex / physiology*
  • Child
  • Evoked Potentials / physiology*
  • Female
  • Functional Laterality / physiology
  • Humans
  • Language Tests
  • Male
  • Pattern Recognition, Physiological / physiology
  • Reaction Time / physiology*
  • Recognition, Psychology / physiology
  • Reference Values
  • Speech Discrimination Tests