Evaluation of rubella virus immunoglobulin G (IgG) and IgM assays with the new Vidia instrument

J Clin Microbiol. 2008 May;46(5):1847-9. doi: 10.1128/JCM.00468-08. Epub 2008 Mar 26.

Abstract

For rubella virus immunoglobulin G (IgG) and IgM detection, Vidia assays were compared to Vidas, AxSYM, and Liaison assays with 419 serum samples. Only Vidia produced a sensitivity of 100% for IgG and IgM. Vidia specificities were 98.4% for IgG and 99.8% for IgM, versus Vidas specificities of 100 and 99.3%. Vidia IgG and IgM assays performed equally well.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antibodies, Viral / blood*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Immunoassay / instrumentation
  • Immunoassay / methods*
  • Immunoglobulin G / blood*
  • Immunoglobulin M / blood*
  • Infant
  • Middle Aged
  • Pregnancy
  • Rubella / diagnosis*
  • Rubella / immunology
  • Rubella virus / immunology
  • Rubella virus / isolation & purification*
  • Sensitivity and Specificity

Substances

  • Antibodies, Viral
  • Immunoglobulin G
  • Immunoglobulin M