Two cell lines of t(8;21) acute myeloid leukemia with activating KIT exon 17 mutation: models for the 'second hit' hypothesis

Leukemia. 2008 Sep;22(9):1792-4. doi: 10.1038/leu.2008.61. Epub 2008 Apr 3.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Chromosomes, Human, Pair 21
  • Chromosomes, Human, Pair 8
  • Exons
  • Humans
  • Leukemia, Myeloid, Acute / etiology*
  • Leukemia, Myeloid, Acute / genetics
  • Leukemia, Myeloid, Acute / pathology
  • Models, Biological
  • Mutation
  • Proto-Oncogene Proteins c-kit / genetics*
  • Translocation, Genetic

Substances

  • Proto-Oncogene Proteins c-kit