Comparison of ropivacaine and lidocaine for paracervical block during surgical abortion

Contraception. 2008 May;77(5):382-5. doi: 10.1016/j.contraception.2008.01.009. Epub 2008 Mar 21.

Abstract

Background: The study was conducted to compare the effectiveness of ropivacaine and lidocaine as paracervical analgesia for elective abortion by vacuum aspiration.

Study design: This single-center double-blinded randomized study tested two different agents for paracervical analgesia in elective abortions: lidocaine (n=57) or ropivacaine (n=57). We assessed intra- and postoperative pain according to both a visual analogical scale rated from 0 to 10 and postoperative analgesic requirements.

Results: Mean intraoperative pain was significantly lower in the ropivacaine group (5.23+/-2.72 vs. 4.18+/-2.77, p=.048.). There was no significant difference in mean assessed pain at the end of the intervention or at 2 or 4 h afterward. The rate of subjects requiring additional postoperative analgesia did not differ significantly between the lidocaine and ropivacaine groups [8/59 (13.5%) vs. 6/59 (10.1%), p=.33].

Discussion: Intraoperative pain appears to be less with ropivacaine than with lidocaine. Nonetheless, the clinical difference was slight, as was therefore the benefit of using ropivacaine for paracervical block in elective abortions.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abortion, Induced*
  • Adult
  • Amides / administration & dosage*
  • Anesthesia, Obstetrical*
  • Anesthetics, Local / administration & dosage*
  • Autonomic Nerve Block
  • Cervix Uteri / innervation
  • Double-Blind Method
  • Female
  • Humans
  • Lidocaine / administration & dosage*
  • Pain, Postoperative / prevention & control*
  • Ropivacaine
  • Treatment Outcome
  • Vacuum Curettage

Substances

  • Amides
  • Anesthetics, Local
  • Ropivacaine
  • Lidocaine