Pediatric hypothyroidism presenting with a polymyositis-like syndrome and increased creatinine: report of three cases

Anne Marie Sbrocchi; Gaëlle Chédeville; Rosie Scuccimarri; Ciarán M Duffy; Preetha Krishnamoorthy

doi:10.1515/jpem.2008.21.1.89

Pediatric hypothyroidism presenting with a polymyositis-like syndrome and increased creatinine: report of three cases

J Pediatr Endocrinol Metab. 2008 Jan;21(1):89-92. doi: 10.1515/jpem.2008.21.1.89.

Authors

Anne Marie Sbrocchi¹, Gaëlle Chédeville, Rosie Scuccimarri, Ciarán M Duffy, Preetha Krishnamoorthy

Affiliation

¹ Department of Pediatrics, Divisions of Rheumatology and Endocrinology, Montreal Children's Hospital, McGill University Health Center, McGill University, Montreal, Quebec, Canada.

PMID: 18404977
DOI: 10.1515/jpem.2008.21.1.89

Abstract

We report three pediatric cases of primary hypothyroidism presenting with musculoskeletal complaints, elevated muscle enzymes and increased creatinine. Thyroid hormone replacement led to improvement in both the clinical features and laboratory abnormalities.

Publication types

Case Reports

MeSH terms

Child
Creatinine / metabolism*
Diagnosis, Differential
Female
Humans
Hypothyroidism / complications
Hypothyroidism / diagnosis*
Hypothyroidism / metabolism
Male
Polymyositis / complications
Polymyositis / diagnosis*
Polymyositis / metabolism
Syndrome
Thyroid Function Tests

Substances

Creatinine