Ovarian signet-ring stromal tumor: a potential diagnostic pitfall

Int J Surg Pathol. 2008 Apr;16(2):180-4. doi: 10.1177/1066896907304627.

Abstract

Signet-ring stromal tumor is a rare ovarian neoplasm with only 10 reported cases in the literature. We report an unusual case of ovarian signet-ring stromal tumor in a 69-year-old woman who presented with right adnexal mass and underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. The diagnosis was based on histological, histochemical, immunohistochemical, and electron microscopy characteristics. The main significance is to differentiate this benign tumor from the highly malignant Krukenberg tumor, and this differential diagnosis is discussed.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biomarkers, Tumor / analysis
  • Carcinoma, Signet Ring Cell / chemistry
  • Carcinoma, Signet Ring Cell / diagnosis*
  • Carcinoma, Signet Ring Cell / surgery
  • Cytoplasm / ultrastructure
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunohistochemistry
  • Krukenberg Tumor / diagnosis
  • Ovarian Neoplasms / chemistry
  • Ovarian Neoplasms / diagnosis*
  • Ovarian Neoplasms / surgery
  • Stromal Cells / chemistry
  • Stromal Cells / pathology*
  • Stromal Cells / ultrastructure
  • Treatment Outcome

Substances

  • Biomarkers, Tumor